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Test- EEG Monitoring Concerningly Underutilized In Clinical TrialsClinical Research News | Study sponsors making choices about if, when, and how to include brain monitoring in their clinical studies do not often ground those choices in science or optimize for subject safety and trial de-risking.The key problem is a lack of electroencephalogram (EEG) expertise with no guidance from the Food and Drug Administration […]
- Bridging Beyond Infectious Diseases: A Shift in Focus for African Clinical SitesClinical Research News | Africa faces a dual healthcare challenge with the persisting burden of infectious diseases and the escalating prevalence of non-communicable diseases (NCDs). This shifting paradigm underscores the urgent need for African research sites to broaden their focus beyond infectious diseases and engage more robustly in NCD clinical research, with sponsors playing a […]
- Citizen-Driven Research Aids Development Of Digital Biomarkers For ALSClinical Research News | When it comes to research on amyotrophic lateral sclerosis (ALS), every stakeholder—most especially patients—knows time is of the essence. From diagnosis to death, life expectancy from the debilitating neuromuscular disease can be two years or less.
- Trial Begins For ‘Probabilistic Approach’ To Diagnosing Ovarian CancerClinical Research News | Scientists in the Georgia Tech Integrated Cancer Research Center (ICRC) are proposing a new, more realistic approach to diagnosing cancer that provides a probabilistic statement about the likelihood of developing it, much like how cholesterol tests are used to assess heart disease risk. Probabilities are based on an individual’s metabolic profile […]
- Biology-Based Diagnostic Criteria For Parkinson’s Disease ResearchClinical Research News | Scientists from a trio of countries are calling for a new, more comprehensive way of classifying Parkinson’s disease for diagnostic research purposes that considers an individual’s biology. The disorder might thereby be detected before patients have any symptoms, as is now the case for cancer and diabetes.
- Proteomics Approach Working Its Way To The Clinic For Stubborn CancersClinical Research News | For roughly half of patients with recurrence of often-deadly glioblastoma multiforme (GBM), their tumors are characterized by cells that look a lot like healthy neurons. The mimicry trick was discovered by proteomics, which has opened a view to tumor alterations unavailable through genetics alone.
- ‘Fragmentomics’ Approach Catches Cancers Earlier In The BloodClinical Research News | A machine learning method dubbed A-PLUS (Alu Profile Learning Using Sequencing) recently demonstrated its ability to pick up cancers earlier and with smaller blood draws than is required for whole genome sequencing. This makes possible a future where people might get annual blood draws to check for cancer based on the […]
- SEQSTER Selected By MSAA, Owkin Expands Collaboration With Sanofi, Thermo Fisher Scientific Launches New Clinical Registry, MoreClinical Research News | SEQSTER has been selected by the Multiple Sclerosis Association of America (MSAA) for its patient-centricity, 1-Click Records, and cutting-edge longitudinal health record; Owkin adds immunology to Sanofi collaboration; Thermo Fisher Scientific launches a new CorEvitas syndicated clinical registry in generalized pustular psoriasis; and more.
- Follow the Money: Cystic Fibrosis Treatment, Advancing CAR-T Candidate, Modular T Cell Engagers, MoreClinical Research News | Sionna Therapeutics plan to develop a first-in-class small molecules designed to fully restore the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein by stabilizing the first nucleotide-binding domain (NBD1); Capstan Therapeutics is advancing CPTX2309, the company’s lead in vivo chimeric antigen receptor T cell (CAR-T) candidate, to early clinical […]
- Electronic White Blood Cell Tracker Developed For Near-Patient TestingClinical Research News | A revolution is underway in the diagnostics world that is reminiscent of what transpired in the computing field before the advent of PCs and smartphones. The unimagined possibilities of today will come from democratizing technology so that instead of sending patients to the lab, the lab will get sent to patients—and, […]
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